NCT07386431
Not yet recruiting
Not Applicable
The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma
University Medical Centre Ljubljana0 sites30 target enrollmentStarted: February 1, 2026Last updated:
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 30
- Primary Endpoint
- Comparison of gene expression in healthy and with endometriosis affected bowel.
Overview
Brief Summary
The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma. The study will include patients for whom surgical treatment of bowel endometriosis is clinically indicated.
This research would represent a significant advancement in evaluating the necessity of surgical intervention in asymptomatic patients or those with mild symptoms. Furthermore, it would provide a broader insight into the systemic impact of endometriosis on other organ systems, ultimately improving risk assessment and preventive measures.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to 18 Years (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Female patients aged 18 and over, treated at the Department of Reproduction for diagnosed deep endometriosis, including bowel endometriosis, for whom surgical treatment is indicated.
Exclusion Criteria
- •Patients with known inflammatory bowel disease (IBD), patients with a personal history of gynecological or gastrointestinal malignancy
Outcomes
Primary Outcomes
Comparison of gene expression in healthy and with endometriosis affected bowel.
Time Frame: 3 years
Secondary Outcomes
No secondary outcomes reported
Investigators
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