The effect of tapering of prednisolone after pulse therapy in a MS attack
Phase 3
Recruiting
- Conditions
- Multiple sclerosis.Multiple sclerosis
- Registration Number
- IRCT20120314009297N6
- Lead Sponsor
- Sari University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Age over 18 years
Disability Status Scale (EDSS) 0 to 5.0 before the attack
Exclusion Criteria
Corticosteroid susceptibility
Any worsening in symptoms that require a change in treatment
Patient with optic neuritis
Not complete Period of treatment by the patient
A patient with active and bleeding stomach ulcer
A patient with diabetes with uncontrolled blood sugar
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method EDSS (Expanded Disability Status Scale)and FSS(Functional Systems Scores) assessments that sustained increase in EDSS is considered as a change in measure from the start of the study. These two measures ultimately assess the incapacity of the MS and the course of the disease after receiving treatment. Timepoint: The first month and the third month. Method of measurement: FSS, EDSS scale.
- Secondary Outcome Measures
Name Time Method Pulse methylprednisolone followed by oral prednisone Safety Assessment. Timepoint: The end of the first month. Method of measurement: Check list ARMS (assessment of relapse in multiple Sclerosis).