A clinical trial to study the effects of three drugs, Mephentermine, Ephedrine and Phenylephrine on Post Subarachnoid Block Hypotension during Lower Segment Caesarean Section (LSCS).
Phase 4
- Conditions
- Health Condition 1: null- Pregnant women
- Registration Number
- CTRI/2015/10/006255
- Lead Sponsor
- Govt Medical College Department of Pharmacology Bhavnagar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
ASA 1 or 2 women with term, uncomplicated, singleton pregnancy scheduled to undergo elective and emergency caesarean section
- Systolic blood pressure: 100 to 150 mm of Hg
- Diastolic blood pressure: 70 to 90 mm of Hg
Exclusion Criteria
- Patient refusal to participate in study
- Absolute and relative contraindication to spinal anesthesia
- Pregnancy induced hypertension, pre-eclampsia, eclampsia etc..
- CVS (e.g. valvular heart disease) and CNS(e.g. cv stroke) abnormalities
- Diabetes Mellitus (Random blood sugar >140 mg/dl)
- Fetal (e.g. macrocephaly) and placental abnormalities(e.g. placenta previa)
- Sensitivity to local anaesthetic agent used in study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method