Exploring the effect of the supplement AB070597 in humans with declining kidney functio
Not Applicable
Completed
- Conditions
- Urological and Genital DiseasesDeclining renal function in chronic kidney diseaseChronic kidney disease, chronic renal failure
- Registration Number
- ISRCTN44802329
- Lead Sponsor
- Whitsell Innovations
- Brief Summary
2020 results in https://doi.org/10.15520/jcmro.v3i11.367 (added 04/12/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 5
Inclusion Criteria
1. Aged 63 to 80 years
2. White
3. Male
4. Under concurrent medical care in the United States
5. Chronic kidney disease (CKD) or an estimated glomerular filtration rate (eGFR) decline rate of =4 ml/min/1.73 m² over the previous 24 months
6. History of increasing blood-serum creatinine from CKD or as a consequence of aging
Exclusion Criteria
1. Concurrent or suspected comorbidities unrelated to CKD
2. Diabetic
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Estimated glomerular filtration rate (eGFR) calculated from participant age and blood-serum creatinine concentration at baseline, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, and 12 months<br> 2. Individual eGFR median-rate-of-change per unit time compared to eGFR medium-rate-of-change per unit time of 2870 chronic kidney disease participants in a study by Tsai CW, et al. (2017) using non-parametric one-sample Wilcoxon signed-rank test<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Estimated glomerular filtration rate measured by blood-serum creatinine and age at baseline, 12, 34, and 36 weeks<br><br>