A prospective, observational study investigating the molecular and cellular responses to traumatic injury (and resuscitation) in severely injured and bleeding adults and children and how these influence patient outcomes such as mortality, organ dysfunction, blood transfusion requirements and quality of life: Activation of Coagulation and Inflammation in Trauma II
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 入组人数
- 5,000
研究概览
简要总结
2015 Abstract results in http://doi.org/10.1186/1757-7241-23-s2-a8 (added 31/03/2021) 2020 Interim results article in http://doi.org/10.1097/SLA.0000000000003771 (added 31/03/2021) 2014 Interim results article in http://doi.org/10.1097/TA.0000000000000146 (added 31/03/2021) 2013 Interim results article in http://doi.org/10.1097/SHK.0b013e31828ded41 (added 31/03/2021) 2019 Interim results article in http://doi.org/10.1097/SLA.0000000000002733 (added 31/03/2021) 2013 Interim results article in http://doi.org/10.1097/ta.0b013e3182788b0f (added 31/03/2021) 2017 Interim results article in http://doi.org/10.1097/ALN.0000000000001428 (added 31/03/2021) 2015 Interim results article in http://doi.org/10.1007/s00134-014-3584-1 (added 31/03/2021) 2012 Interim results article in https://doi.org/10.1111/jth.12078 (added 31/03/2021) 2021 Interim results article in http://doi.org/10.1097/sla.0000000000003657 (added 31/03/2021) Interim results article in https://doi.org/10.1002/bjs.8728 (added 31/03/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34724559/ Secondary analysis (added 02/11/2021)
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •All trauma patients regardless of age can be screened for inclusion in hospital (adults only in prehospital care)
排除标准
- •1. Transfers from other hospitals
- •2. Burns > 5% total body surface area
- •3. More than 120 mins have lapsed since time of injury
- •4. Deemed inappropriate for recruitment by an independent clinician