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Clinical Trials/NCT01794598
NCT01794598
Terminated
Not Applicable

HF-ACTION Depression Education Substudy

Duke University0 sites270 target enrollmentMay 2004

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Heart Failure
Sponsor
Duke University
Enrollment
270
Primary Endpoint
Change in recognition of study participant to depression care
Status
Terminated
Last Updated
11 years ago

Overview

Brief Summary

Purpose of the Study: The significant impact of depression on the poor prognosis and functional restrain, recognition and successful treatment of depression in patients with Chronic Heart Failure (CHF) may result in improvement of overall outcome of those patients. However, depression comorbid with CHF has been overlooked in the real practice. Therefore, the investigators are proposing a study to 1) assess the prognostic impact of depression in patients with stable CHF who have been managed as outpatients, and 2) assess whether provision of depression education to CHF patients will improve the care of depression.

Patients with chronic heart failure are enrolled into this study with a half of them are randomly assigned to receive a packet of depression education materials and then other half not. Participants and investigators both are blinded to the assignment. All the participants are provided a toll free phone number to contact the research team as needed. Depressive symptoms and patients knowledge of depression are assessed at baseline prior to randomization and at 1-month and 6-month following the enrollment.

Responses of the study participants, such as change of depressive symptoms, and requests for psychiatric help are examined between two groups.

Registry
clinicaltrials.gov
Start Date
May 2004
End Date
December 2006
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Inclusion Criteria
  • LVEF ≤ 35%.
  • NYHA class II, III, or IV heart failure for the previous three months despite a minimum of 6 weeks of treatment.
  • Must be on optimal heart failure therapy according to AHA/ACC and HFSA heart failure guidelines, including treatment with ACEI and beta-blocker therapy, or have documented rationale for variation, including intolerance, contraindication, patient preference, or personal physician's judgment.

Exclusion Criteria

  • Age less than
  • Currently pregnant or intending to become pregnant in the next year.
  • Cardiovascular procedure or hospitalization for any reason planned in the next 6 months.
  • Expectation of receiving a cardiac transplant in the next six months.
  • Unable to provide the study consent.
  • Participation another clinical trial(s) that may interfere with follow-up or data collection for this study, or that may affect cardiovascular mortality.

Outcomes

Primary Outcomes

Change in recognition of study participant to depression care

Time Frame: Baseline, 1 month and 6 months

To assess whether the provision of depression education materials will increase knowledge of the impact depression has on Congestive Heart Failure patients. This will be measured through study participants completion of a questionnaire to record their views on depression and depression care in a non-psychiatric setting.

Secondary Outcomes

  • Change in response of study participant to depression care(Baseline, 1 month, and 6 months)

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