A home-based, multidisciplinary liver optimisation program for the first 28 days after an admission for acute-on-chronic liver failure (LivR Well)

Monash Health0 个研究点目标入组 104 人开始时间: 2021年12月13日最近更新: 2024年7月8日

适应症

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•Adult patients
•Acute hepatic decompensation characterised by ascites, variceal haemorrhage, hepatorenal syndrome, hepatic encephalopathy, jaundice
•Diagnosis of acute-on-chronic liver failure (ACLF) using the European Foundation of the Study of Liver Failure using the Chronic Liver Failure criteria (EF-CLIF) and which includes age and white cell count. Severity is graded according to the number of organ failures
•Requiring consultation from at least 3 allied health clinicians

•Greater than grade 2 hepatic encephalopathy
•Severe chronic extrahepatic disease
•Human immunodeficiency virus (HIV) or ongoing immunosuppressive treatments
•Admission for scheduled procedure or treatment
•Moribund or receiving end-of-life care
•Active malignancy including hepatocellular carcinoma
•Receiving regular albumin infusions for treatment of chronic hepatorenal syndrome (excluding those for periprocedural circulatory support following large volume paracentesis)
•Refractory ascites managed with a intra-peritoneal catheter in-situ
•Inability to provide informed consent
•Residing outside the local hospital service catchment or deemed ineligible for home visits due to staff safety or occupational hazard concerns
•Residing in a residential aged care facility

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