Comparison of Drugs like Dexmedetomidine and Fentanyl on emergence agitation and recovery after inhalational agent-sevoflurane anesthesia in children

Completed

• Conditions: Healthy ASA PS I &II pediatric patients

• Registration Number: CTRI/2018/05/013850
• Lead Sponsor: Dept of Anesthesiology Medical college Baroda

Brief Summary

In our study we found it appropriate to compare the  effect of a short acting opioid Fentanyl with the new selective α2-adrenergic receptor agonist Dexmedetomidine given immediately after intubation,  to reduce emergence agitation and also observe the recovery characteristics in children aged 3-10 years after Sevoflurane anaesthesia

Detailed Description

Not available

Study Timeline

• Study Start: 2013-06-19
• Study Completion: 2014-12-27
• Last Update Posted: 2018-04-05

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

•60 children of ASA I/II •Type of surgery- Orchidopexy Circumcision Hypospadiasis repair Congenital hernia/ hydrocele repair.

Exclusion Criteria

•Children <3yrs and >10 yrs •Patients with URTI, asthma •Anticipated difficult intubation •Cardio respiratory, hepatic, renal dysfunction •H/O of allergy to the drugs used •H/O any sedative drugs used.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To observe the effect of IV Dexmedetomidine and IV Fentanyl in attenuation of emergence agitation after Sevoflurane anaesthesia in children using Five Point Emergence Agitation Scale.	To observe the effect of IV Dexmedetomidine and IV Fentanyl in attenuation of emergence agitation after Sevoflurane anaesthesia in children using Five Point Emergence Agitation Scale at every 15 minutes upto 120 minutes.

Secondary Outcome Measures

Name	Time	Method
1.To observe the recovery profile using Modified Aldrete Recovery Score.	2.To observe haemodynamic and respiratory parameters perioperatively.

Trial Locations

Locations (1)

Medical college & S.S.G.Hospital, Baroda; 🇮🇳 Vadodara, GUJARAT, India

Medical college & S.S.G.Hospital, Baroda

🇮🇳Vadodara, GUJARAT, India

Dr Mamta G Patel

Principal investigator

9825453024

mgpatel111@yahoo.com