Left Elective Colectomy in Renal Transplanted Patients

Completed

• Conditions: Left Elective Colectomy; Renal Transplanted Patients
• Interventions: Procedure: Left elective colectomy

• Registration Number: NCT04495023
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Aim of the study :

To evaluate postoperative outcomes of elective left-sided colectomy in a renal transplanted population.

Methods :

From 2010 to 2015, all consecutive patients who underwent left elective colectomy in a referral center were prospectively collected.

Considering our exclusion criterial, data from 120 patients were analyzed. The cohort was separated into 2 groups : renal transplanted patients (KTR-group) and non-renal transplanted patients (C-group) Short and longterm outcomes were compared between the two groups.

Primary outcome :

90 days postoperative anastomotic leak rate

Detailed Description

From January 2010 to December 2015, data from patients requiring an elective left colectomy for benign or malignant indication were collected prospectively in our colorectal surgery database.

According to our exclusion criterial patients were retrospectively divided into two groups: kidney transplant recipients (KTR-group) and control group (C-group).

The surgical indication for an oncologic left colectomy was retained by the expert surgeon, after a multidisciplinary conversation meeting comprising at least one surgeon, one gastroenterologist, one nephrologist, one radiologist and one oncologist. The surgical indication for diverticular disease was based on French guidelines.

Demographic, clinical, intraoperative and postoperative, histological, length of hospital stay and mortality data were collected over a 90-day period following the intervention.

Study Timeline

• Study Start: 2020-01-01
• Primary Completion: 2020-01-30
• Study Completion: 2020-04-01
• Status Verified: 2020-07
• Study First Submitted: 2020-07-28
• Study First Submitted QC: 2020-07-28
• Study First Posted: 2020-07-31
• Last Update Submitted: 2020-09-01
• Last Update Posted: 2020-09-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1 (Kidney transplanted patients)	Left elective colectomy	Group 1: Kidney transplanted patients requiring oncologic or non-oncologic left elective colectomy All kidney transplanted patients requiring oncologic or non-oncologic left elective colectomy between 01 January 2004 and 31 December 2015.
Group 2 (Non-transplanted patients)	Left elective colectomy	Group 2 : Non-transplanted patients requiring oncologic or non-oncologic left elective colectomy Non-transplanted patients requiring oncologic or non-oncologic left elective colectomy between 01 January 2004 and 31 December 2015.

Primary Outcome Measures

Name	Time	Method
Rate of Anastomotic leak after left elective colectomy	90 days postoperative	Anastomotic leak according to the International Study Group of Rectal Cancer

Secondary Outcome Measures

Name	Time	Method
Long term outcomes	1 day	Status at the date of latest news

Trial Locations

Locations (1)

Uhmontpellier; 🇫🇷 Montpellier, France