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Role of MRI Breast in Detection of Ductal Carcinoma in Situ

Active, not recruiting
Conditions
Carcinoma in Situ
Registration Number
NCT06744140
Lead Sponsor
Superior University
Brief Summary

"This study investigates the role of Magnetic Resonance Imaging (MRI) in detecting Ductal Carcinoma in situ (DCIS) in high-risk breast cancer patients.

Detailed Description

Improved detection rates of DCIS in high-risk patients. Enhanced diagnostic accuracy, reducing false positives and negatives. Ductal Carcinoma in situ (DCIS) is a non-invasive breast cancer where abnormal cells are confined to the milk ducts.

The Breast Imaging Reporting and Data System (BI-RADS) is a standardized scoring system used to classify breast imaging findings. Scores range from 0 (incomplete) to 6 (known biopsy-proven malignancy)."

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
35
Inclusion Criteria
  • High-risk breast cancer patients with a family history of breast cancer or genetic predispositions (e.g., BRCA mutations).
  • Patients aged 30-65 years.
  • Patients willing to undergo breast MRI screening for DCIS detection.
Exclusion Criteria
  • Patients with contraindications to MRI imaging (e.g., pacemakers, claustrophobia).
  • Patients with a history of prior breast surgery or interventions that may interfere with imaging interpretation.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
sensitivity & specificity12 Months

sensitivity \& specificity of MRI in detecting DCIS

BIRADS scores12 Months

BIRADS scores will be used to evaluate the diagnostic accuracy of MRI in detecting DCIS

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

INMOL hospital

🇵🇰

Lahore, Punjab, Pakistan

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