Role of MRI Breast in Detection of Ductal Carcinoma in Situ
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
- Superior University
- Enrollment
- 35
- Locations
- 1
- Primary Endpoint
- sensitivity & specificity
Study Overview
Brief Summary
"This study investigates the role of Magnetic Resonance Imaging (MRI) in detecting Ductal Carcinoma in situ (DCIS) in high-risk breast cancer patients.
Detailed Description
Improved detection rates of DCIS in high-risk patients. Enhanced diagnostic accuracy, reducing false positives and negatives. Ductal Carcinoma in situ (DCIS) is a non-invasive breast cancer where abnormal cells are confined to the milk ducts.
The Breast Imaging Reporting and Data System (BI-RADS) is a standardized scoring system used to classify breast imaging findings. Scores range from 0 (incomplete) to 6 (known biopsy-proven malignancy)."
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 30 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •High-risk breast cancer patients with a family history of breast cancer or genetic predispositions (e.g., BRCA mutations).
- •Patients aged 30-65 years.
- •Patients willing to undergo breast MRI screening for DCIS detection.
Exclusion Criteria
- •Patients with contraindications to MRI imaging (e.g., pacemakers, claustrophobia).
- •Patients with a history of prior breast surgery or interventions that may interfere with imaging interpretation.
Outcomes
Primary Outcomes
sensitivity & specificity
Time Frame: 12 Months
sensitivity \& specificity of MRI in detecting DCIS
BIRADS scores
Time Frame: 12 Months
BIRADS scores will be used to evaluate the diagnostic accuracy of MRI in detecting DCIS
Secondary Outcomes
No secondary outcomes reported
Investigators
Muhammad Naveed Babur
Principal Investigator
Superior University