The Vanderbilt University

🇺🇸United States

Country: 🇺🇸United States

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Clinical Trials

The Clonal Hematopoiesis & Inflammation in Vasculature Registry and Biorepository

Recruiting

Conditions: Clonal Hematopoiesis

First Posted Date: 2024-11-22

Last Posted Date: 2024-11-22

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 800

Registration Number: NCT06701214

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

Biomarker Platform (Virtual Nodule Clinic) for the Management of Indeterminate Pulmonary Nodules

Not Applicable

Recruiting

Conditions: Lung Neoplasm

First Posted Date: 2024-10-15

Last Posted Date: 2024-11-07

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 400

Registration Number: NCT06638398

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

Not Applicable

Recruiting

Conditions: Stage I Lung Cancer
Stage II Lung Cancer

Interventions: Procedure: Cryosurgery
Procedure: Robotic Bronchoscopy
Procedure: Bronchoscopy with Biopsy
Procedure: Resection
Procedure: Chest Radiography
Procedure: Computed Tomography
Procedure: Biospecimen Collection
Other: Electronic Health Record Review

First Posted Date: 2024-09-19

Last Posted Date: 2024-11-08

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 30

Registration Number: NCT06593106

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

Cohort to Augment the Understanding of Sarcoma Survivorship Across the Lifespan

Recruiting

Conditions: Sarcoma

Interventions: Other: Surveys
Other: Blood Collection
Other: Saliva Collection
Other: Urine Collection
Other: Stool Collection
Other: Tissue collection
Other: Physical Activity Monitoring

First Posted Date: 2024-07-01

Last Posted Date: 2024-07-01

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 2100

Registration Number: NCT06482957

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia

Phase 1

Recruiting

Conditions: Relapsed Myelodysplastic Syndrome
Refractory Myelodysplastic Syndrome
Acute Myeloid Leukemia
Recurrent Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia

Interventions: Drug: Eltanexor
Drug: Venetoclax
Procedure: Bone Marrow Aspiration and Biopsy
Procedure: Biospecimen Collection

First Posted Date: 2024-05-06

Last Posted Date: 2024-10-17

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 60

Registration Number: NCT06399640

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer

Phase 2

Recruiting

Conditions: Stage I Lung Cancer
Stage II Lung Cancer
Limited Stage Lung Small Cell Carcinoma
Stage III Lung Cancer

Interventions: Drug: Cisplatin
Drug: Carboplatin
Drug: Etoposide
Biological: Pembrolizumab
Procedure: Computed Tomography
Procedure: Positron Emission Tomography
Procedure: Magnetic Resonance Imaging
Procedure: Biospecimen Collection
Radiation: Radiation Therapy

First Posted Date: 2023-11-20

Last Posted Date: 2024-05-22

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 20

Registration Number: NCT06140407

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation

Phase 1

Recruiting

Conditions: Stage IV Lung Cancer
Extensive Stage Lung Small Cell Carcinoma

Interventions: Drug: Carboplatin
Biological: Atezolizumab
Drug: Etoposide
Radiation: Total Body Irradiation
Radiation: Hypofractionated Radiation Therapy
Procedure: Magnetic Resonance Imaging

First Posted Date: 2023-10-31

Last Posted Date: 2024-06-20

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 18

Registration Number: NCT06110572

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

TBNA vs EBUS-TBNA Plus Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing

Phase 3

Recruiting

Conditions: Lung Cancer

Interventions: Procedure: Endobronchial ultrasound with transbronchial needle aspiration
Procedure: Bronchoscopy
Procedure: Cryobiopsy

First Posted Date: 2023-10-30

Last Posted Date: 2024-11-07

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 250

Registration Number: NCT06105801

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

A Combined Biomarker Model for Risk Stratification of Indeterminate Pulmonary Nodules

Recruiting

Conditions: Pulmonary Nodule

Interventions: Procedure: Blood collection
Procedure: Chest Computed Tomography

First Posted Date: 2023-10-10

Last Posted Date: 2024-07-30

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 100

Registration Number: NCT06074133

Locations: 🇺🇸
University of Colorado, Aurora, Colorado, United States
🇺🇸
Rocky Mountain Regional VA Medical Center, Aurora, Colorado, United States
🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

and more 1 locations

Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

Phase 4

Recruiting

Conditions: Digestive System Neuroendocrine Tumor G2
Digestive System Neuroendocrine Tumor G1
Pancreatic Neuroendocrine Tumor G2
Metastatic Digestive System Neuroendocrine Neoplasm
Metastatic Malignant Neoplasm in the Liver
Pancreatic Neuroendocrine Tumor G1

Interventions: Procedure: Tumor Debulking
Drug: Lutetium Lu 177 Dotatate
Procedure: Computed Tomography
Procedure: Magnetic Resonance Imaging
Drug: Copper Cu 64 Dotatate
Procedure: Positron Emission Tomography

First Posted Date: 2023-08-30

Last Posted Date: 2024-07-03

Lead Sponsor: Vanderbilt-Ingram Cancer Center

Target Recruit Count: 6

Registration Number: NCT06016855

Locations: 🇺🇸
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

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