Preoperative Antiseptic in Newborn Circumcision Comparison of Povidone Iodine and Hypochlorous Acid Used

Not Applicable

Completed

• Conditions: Circumcision; Newborn; Infection; Disinfection
• Interventions: Drug: hypochlorous acid

• Registration Number: NCT05175027
• Lead Sponsor: Hisar Intercontinental Hospital

Brief Summary

Comparison of Povidone iodine and Hypochlorous acid used as a Preoperative Antiseptic in Newborn Circumcision abstract

Aim:

Circumcision is one of the most common surgical procedures in all age groups. Before the circumcision procedure, asepsis is provided with a surface disinfectant. Various methods can be used for this process. Povidone iodine, which has been used for years during the transition from traditional circumcision methods to surgical circumcision methods; tissue damage, allergic reactions and increase in pain level. For this reason, the investigators aimed to compare it with Hypochlorous acid (Crystalin), which is a less toxic and more physiological antiseptic solution.

Material and Method:

Newborns to be circumcised randomly were divided into two groups as Hypochlorosis group and Povidone iodine group. At the beginning of the circumcision procedure, a culture was taken in the form of a prepucial swab 1 minute after the cleaning of the local area and the inner surface of the prepuce. Then circumcision was performed. Culture results and complications were compared.

Detailed Description

It is aimed to compare two solutions used for cleaning the operation area in newborn circumcision.It was conducted to compare the antibacterial activity of povidone iodine and hypochlorous.

Study Timeline

• Study Start: 2021-05-05
• Primary Completion: 2021-10-30
• Study Completion: 2021-11-11
• Study First Submitted: 2021-11-11
• Status Verified: 2021-12
• Study First Submitted QC: 2021-12-30
• Last Update Submitted: 2021-12-30
• Study First Posted: 2022-01-03
• Last Update Posted: 2022-01-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

• male
• newborn,

Exclusion Criteria

• hipospadias,
• epispadias,
• urinary infectious

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
Povidone iodine	hypochlorous acid	Povidone iodine was used as an antiseptic for the patients
Hypochlorosis	hypochlorous acid	Hypochlorosis was used as an antiseptic for the patients

Primary Outcome Measures

Name	Time	Method
The effect of both drugs on wound healing will be investigated.	one month	there is wound healing;1,no wound healing:0
The effect of both drugs on antibacterial effects will be investigated	one week	there is bacterial growth:1, there is no bacterial growth:0

Trial Locations

Locations (1)

Hisar Intercontinental Hospital; 🇹🇷 Istanbul, Turkey