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CASE WESTERN RESERVE UNIVERSITY

CASE WESTERN RESERVE UNIVERSITY logo
🇺🇸United States
Ownership
Private
Established
1826-01-01
Employees
5K
Market Cap
-
Website
https://case.edu/dental

Clinical Trials

155

Active:8
Completed:107

Trial Phases

6 Phases

Early Phase 1:1
Phase 1:5
Phase 2:5
+3 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (139 trials with phase data)• Click on a phase to view related trials

Not Applicable
121 (87.1%)
Phase 1
5 (3.6%)
Phase 2
5 (3.6%)
Phase 4
4 (2.9%)
Phase 3
3 (2.2%)
Early Phase 1
1 (0.7%)

Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia

Not Applicable
Not yet recruiting
Conditions
Spinal Cord Injury Cervical
Spinal Cord Injuries (Complete and Incomplete)
First Posted Date
2025-11-06
Last Posted Date
2025-11-06
Lead Sponsor
Case Western Reserve University
Target Recruit Count
3
Registration Number
NCT07225582
Locations
🇺🇸

Case Western Reserve University, Cleveland, Ohio, United States

Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years

Not Applicable
Not yet recruiting
Conditions
Fuchs Endothelial Corneal Dystrophy
Corneal Endothelial Decompensation
First Posted Date
2025-10-15
Last Posted Date
2025-10-15
Lead Sponsor
Case Western Reserve University
Target Recruit Count
570
Registration Number
NCT07217249
Locations
🇺🇸

Price Vision Group, Indianapolis, Indiana, United States

🇺🇸

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

🇺🇸

University of Michigan/Kellogg Eye Center, Ann Arbor, Michigan, United States

and more 2 locations

Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER)

Not Applicable
Not yet recruiting
Conditions
Elder Mistreatment
Elder Abuse
Quality of Care
Dementia
Caregiving
First Posted Date
2025-10-15
Last Posted Date
2025-10-15
Lead Sponsor
Case Western Reserve University
Target Recruit Count
260
Registration Number
NCT07216950
Locations
🇺🇸

Case Western Reserve University, Cleveland, Ohio, United States

Youth Empowerment and Safety Intervention

Not Applicable
Not yet recruiting
Conditions
Suicide
Self-Injurious Behavior
First Posted Date
2025-10-09
Last Posted Date
2025-10-09
Lead Sponsor
Case Western Reserve University
Target Recruit Count
60
Registration Number
NCT07214233

LT Comparative Effectiveness of 2 Caries Treatments

Not Applicable
Recruiting
Conditions
Dental Caries
First Posted Date
2025-10-09
Last Posted Date
2025-11-13
Lead Sponsor
Case Western Reserve University
Target Recruit Count
480
Registration Number
NCT07213661
Locations
🇺🇸

Case Western Reserve University, Cleveland, Ohio, United States

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News

NervGen Pharma Secures $10 Million Funding to Advance First-in-Class Spinal Cord Injury Therapy NVG-291

NervGen Pharma announced a $10 million private placement to advance NVG-291, a first-in-class therapeutic peptide targeting nervous system repair for spinal cord injury.

Gabapentin Linked to Increased Dementia Risk in Chronic Pain Patients

A large medical records study found that receiving six or more gabapentin prescriptions for chronic low back pain was associated with 29% increased dementia risk and 85% increased mild cognitive impairment risk within 10 years.

NervGen Appoints Randall Kaye as Chief Medical Advisor Following Positive Spinal Cord Injury Trial Results

NervGen Pharma has appointed Dr. Randall Kaye as Chief Medical Advisor to guide the clinical and regulatory strategy for NVG-291, following positive topline results from the chronic cohort of their Phase 1b/2a spinal cord injury trial.

NSF Awards $500K Grant to Advance Synthetic DNA Nanoparticles for Targeted Gene Therapy

Dr. Divita Mathur at Case Western Reserve University received a prestigious NSF CAREER grant to develop synthetic DNA nanoparticles that can deliver therapeutic genes with precise targeting capabilities.

Trailhead Biosystems Secures $20M to Advance iPSC Technology for Drug Discovery and Regenerative Medicine

Trailhead Biosystems has raised $20 million in funding led by MAK Capital to enhance its portfolio of induced pluripotent stem cell (iPSC) derived cells for research applications.

American Heart Association Awards $1M to Study GLP-1 Medications' Impact on Cardiovascular Risk

The American Heart Association has funded seven research projects with $1 million to identify which patients with obesity and cardiovascular disease benefit most from GLP-1/GIP medications.

Semaglutide Shows Promise for Slowing Biological Aging and Improving Cognition in HIV Patients

Semaglutide treatment slowed biological aging by approximately 9% and reduced epigenetic aging mortality risk by three years in HIV patients with lipohypertrophy over 32 weeks.

FDA Clears First Wireless, Catheter-Free Urodynamics System for Bladder Dysfunction Testing

The FDA has granted 510(k) clearance to Bright Uro's Glean™ Urodynamics System, the first wireless, catheter-free device for monitoring bladder dysfunction in patients with lower urinary tract conditions.

Novel Screening Technologies Enter Clinical Trial to Detect Silent Esophageal Precancer

University Hospitals and Case Western Reserve University launch an $8 million NIH-funded clinical trial to evaluate EsoCheck and EsoGuard technologies for detecting Barrett's Esophagus in non-GERD patients.

MedPacto Advances Vactosertib to Phase 2 Trial for Pediatric Osteosarcoma Treatment in US

MedPacto partners with leading US institutions, including Stanford University and Case Western Reserve University, to conduct Phase 2 trial of vactosertib for pediatric osteosarcoma treatment.

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