Evaluation of efficacy of hyaluronic acid, i-PRF and combination of both through VISTA approach in the management of thin periodontal phenotype- A Randomized clinical trial ( RCT)
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 69
- 试验地点
- 1
- 主要终点
- To evaluate the efficacy of Hyaluronic acid, i-PRF and combination of both through VISTA approach on thin periodontal phenotype.
研究概览
简要总结
This is a randomized clinical trial, which studies effects of 1.5% hyaluronic acid, i- PRF and combination of both on thin periodontal phenotype through VISTA approach for gingival thickness, keratinized tissue width and buccal bone thickness. The study evaluates primary hypothesis as is there difference in efficacy of hyaluronic acid, i-PRF and combination of both through VISTA approach in the management of thin periodontal phenotype in terms of gingival thickness, keratinized tissue width and buccal bone thickness.
The primary outcome measures will be increase in gingival thickness, keratinized tissue width and buccal bone thickness. Improvement in gingival index, plaque index, bleeding on probing, probing pocket depth and clinical attachment levels will be secondary outcome that will be measured at baseline, one month, three months and six months. Buccal bone thickness will be measured at baseline and six months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Participants diagnosed with thin gingival phenotype.
- •gingival thickness less than or equal to 1 mm 2 Participants willing to participate in the study.
排除标准
- •1 Systemically compromised patients 2 Heavy smokers 3 Pregnant or lactating woman 4 Patients who have been previously undergone periodontal therapy 5 Patients with active orthodontic treatment 6 Aggressive or chronic periodontitis 7 Patients with known allergy to hyaluronic acid.
结局指标
主要结局
To evaluate the efficacy of Hyaluronic acid, i-PRF and combination of both through VISTA approach on thin periodontal phenotype.
时间窗: Gingival thickness, Keratinized tissue width at time points baseline, 1 month, 3 months and 6 months. Buccal bone thickness at time points baseline and six months
次要结局
- To evaluate the efficacy of Hyaluronic acid through VISTA approach in the management of thin periodontal phenotype(To evaluate the efficacy of i-PRF through VISTA approach in the management of thin periodontal phenotype)
研究者
Dr Vinita Kothari
Jawahar Medical Foundations Annasaheb Chaudaman Patil Memorial dental college, Dhule