ECG and CMR for Predicting PVCs in Cardiomyopathic Patients
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Assiut University
- Enrollment
- 79
- Primary Endpoint
- Twenty-four hours Holter monitoring after Magnetic Resonance Imaging
Study Overview
Brief Summary
This study aims to assess ECG changes for predicting ventricular arrhythmia in cardiomyopathic patients
Detailed Description
This study aims to assess ECG markers based on 24-hour Holter ECG recordings for predicting ventricular arrhythmia in patients with Structural Heart disease who have left ventricular dysfunction and Left Ventricular Ejection Fraction ≤40%. With special concerns to underlying structural abnormalities in cardiomyopathic patients using Cardiac Magnetic Resonance to determine ventricular function, scar distribution, and grey zone analysis
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 20 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with ischemic and non-ischemic cardiomyopathy, EF < 40 %
- •Patient haemodynamically stable
- •Patients accept to make test
Exclusion Criteria
- •Patients with underlying arrhythmia ex heart block or atrial arrhythmia like PACs, AF.
- •Patients on arrhythmogenic drugs ex digitalis, amiodarone.
- •Patients on underlying Pacemaker device or CRT-D.
- •Patients with MI in less than 40 days
- •Patients refuse to make test .
Outcomes
Primary Outcomes
Twenty-four hours Holter monitoring after Magnetic Resonance Imaging
Time Frame: One year
24 Holter monitoring to detect PVCs burden which is defined as ≥10% of total beats
Secondary Outcomes
No secondary outcomes reported
Investigators
Khaled Mohamed Aly
Resident doctor of cardiology .Luxor International Hospital
Assiut University