Cardiomyopathy Arrhythmia Risk Evaluation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiomyopathy
- Sponsor
- University Health Network, Toronto
- Enrollment
- 164
- Locations
- 1
- Primary Endpoint
- Proportion of patients with appropriate implantable cardioverter defibrillator (ICD) shocks
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This study will evaluate the prognostic utility of novel ECG markers of electrical instability in patients with cardiomyopathy.
Detailed Description
Baseline ECG markers of electrical instability will be measured in patients with cardiomyopathy. These ECG markers will be evaluated from a clinical Holter recording. All patients will have a primary implantable cardioverter defibrillator (ICD) as part of their clinical care. Patients will be followed prospectively for 2 years to evaluate the primary outcome of appropriate ICD shocks. Multivariable modelling will be performed to determine whether the ECG markers of electrical instability independently predict the primary clinical outcome.
Investigators
Eligibility Criteria
Inclusion Criteria
- •cardiomyopathy, primary prevention ICD
Exclusion Criteria
- •brady-pacing requirement
Outcomes
Primary Outcomes
Proportion of patients with appropriate implantable cardioverter defibrillator (ICD) shocks
Time Frame: 2 years
Proportion is from 0 (no patients with shocks) to 100% (all patients receive shocks)