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Clinical Trials/NCT05106530
NCT05106530
Unknown
Not Applicable

Arrhythmogenic Risk Assessment in Coronary Artery Ectasia Patients

Assiut University1 site in 1 country90 target enrollmentJanuary 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Coronary Artery Ectasia
Sponsor
Assiut University
Enrollment
90
Locations
1
Primary Endpoint
Precence of arrhythmias in 24 hours Holter monitoring
Last Updated
4 years ago

Overview

Brief Summary

The investigators thought to explore arrhythmias outcome - hidden arrhythmias, ECG features: Tp-Te interval and Tp-Te/QTc ratio, fQRS among patients with coronary artery ectasia as compared to normal coronary artery patients.

Detailed Description

All patients will be subjected to: A. Full history taking: - Including age, sex, history of DM, HTN, dyslipidemia and Body surface area. B. Holter monitoring for 24 hours: * Heart rate variability * Hidden arrhythmias * Hidden ischemia by monitoring ST segment changes C. Twelve lead ECG: * fQRS in baseline ECG * QT dispersion. * Tp-Te interval and Tp-Te/QTc ratio * Tp-Te dispersion

Registry
clinicaltrials.gov
Start Date
January 1, 2022
End Date
January 1, 2023
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mark Mohsen Nady Kamel

Resident at Cardiology Department

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Subjects with suspected CAD who are referred for elective coronary angiography and/or interventions

Exclusion Criteria

  • Patients with a history of cardiomyopathy and myocardial infarction (MI), left ventricular hypertrophy (LVH), pathological Q wave on ECG, typical left bundle block or right bundle block, incomplete right bundle block, or paced rhythm on ECG.
  • Patients with severe renal impairment
  • Post CABG patients
  • Patients of acute coronary syndrome

Outcomes

Primary Outcomes

Precence of arrhythmias in 24 hours Holter monitoring

Time Frame: 1 year

Incidence of arrhythmias in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients.

Secondary Outcomes

  • • Heart rate variability in Holter monitoring(1 year)
  • • Silent ischemia as detected by Holter(1 years)

Study Sites (1)

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