A Blinded Prospective Study on Development and Validation of the Blood Cell RNA-Based Cancer Detection
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 5,000
- 试验地点
- 1
- 主要终点
- Accuracy of TOO prediction
研究概览
简要总结
Early diagnosis of cancer may provide patients with more treatment options and hopefully prolong survival. The purpose of this multi-center study is to collect peripheral blood from newly diagnosed cancer patients and healthy donors to establish a blood cell RNA-based model for the differentiation of cancer patients and healthy donors. The area under the receiver operating characteristic (AUROC), sensitivity and specificity of the test in the early detection of multiple cancers will be measured.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Accuracy of TOO prediction
时间窗: 1 year
Accuracy of the tissue of origin (TOO) prediction of a blood cell RNA-based cancer detection test
Sensitivity and specificity of cancer detection
时间窗: 1 year
Sensitivity and specificity of the early detection of 30 types of cancers of a blood cell RNA-based cancer detection test
次要结局
未报告次要终点
研究者
Zheng Wang, MD/PhD
Study chair, Clinical Professor
Wuhan Union Hospital, China