Effects of Group Music Therapy Interventions on Alzheimer's Disease Patients: a Three-arm Randomized Controlled Blind Study.

Not Applicable

Completed

• Conditions: Alzheimer's Disease
• Interventions: Other: Passive music therapy; Other: Watching nature videos; Other: Actice music therapy

• Registration Number: NCT04761497
• Lead Sponsor: Universidad Católica San Antonio de Murcia

Brief Summary

The purpose of this study is to determine what type of music therapy (active versus passive) approach has higher effects on clinical symptoms in advanced Alzheimer's disease patients

Detailed Description

Ninety AD patients from six nursing homes participated in the study. Nursing homes were randomly and blindly assigned to receive for three months either active music intervention, passive music listening or usual care. Effects on cognition, behaviour, daily living activities and motor function were assessed after the intervention.

Study Timeline

• Study Start: 2018-09-12
• Primary Completion: 2018-12-19
• Study Completion: 2019-01-07
• Status Verified: 2021-02
• Study First Submitted: 2021-02-12
• Study First Submitted QC: 2021-02-17
• Last Update Submitted: 2021-02-17
• Study First Posted: 2021-02-21
• Last Update Posted: 2021-02-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Nursing-home dwelling
• Diagnosis of probable Alzheimer's disease
• Mild or moderate stage (Clinical Classification of the Dementia)

Exclusion Criteria

• Aphasia
• Hearing impairment that may affect participation in the activities.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
passive music therapy	Passive music therapy	The therapist and the patients were seat listening to the music recorded in a CD. The therapist told patients which the name and the interpreter of each song of the list.
control	Watching nature videos	Patients were watching nature videos for the same duration than the interventions. A therapist was with them facilitating the activity.
active music therapy	Actice music therapy	Each session consisted of: song of welcome (patients had to greet and introduce themselves), rhythmic exercise (three songs were used; therapist and patients kept rhythm by clapping their hands), dance exercises (three songs were used; patients should make free body movements in response to music), game of recognition of songs and interpreters (four songs were used) and song of goodbye.

Primary Outcome Measures

Name	Time	Method
Tinneti scale.Higher scores indicate better motor function	0-3 months. Range 0-28	Motor function
Mini Examination of the Mental State	0-3 months	Cognitive status. Range 0-30. Higher scores indicate better cognition
Barthel index	0-3 months	Functional status. Range 0-100.Higher scores indicate worse functional status
Neuropsychiatric Inventory	0-3 months	Behavioural disorders. Range 0-144. Higher scores indicate greater behavioural problems
Geriatric depression scale	0-3 months	Mood status. Range 0-15. Higher scores indicate worse mood status

Trial Locations

Locations (1)

UCMurcia; 🇪🇸 Murcia, Spain