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Rescue High Frequency Oscillatory Ventilation in Newborns Who Do Not Respond to Conventional Ventilation

Conditions
Acute Mechanical Ventilatory Failure
Interventions
Device: HFOV
Registration Number
NCT02752438
Lead Sponsor
Ankara University
Brief Summary

Although High Frequency Oscillatory Ventilation (HFOV) has been used in case of unresponsive to conventional mechanical ventilation both in children and newborns, there is no data on its success and the factors that affect its success in the literature.

Detailed Description

Although High Frequency Oscillatory Ventilation (HFOV) has been used in case of unresponsive to conventional mechanical ventilation both in children and newborns, there is no data on its success and the factors that affect its success in the literature.

The aim of the study is to define the factors that affect the success of HFOV in newborns who do not respond to conventional mechanical ventilation through an online registry among neonatal intensive care units in Turkey.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
400
Inclusion Criteria
  • patients switched to HFOV in case of unresponse to conventional ventilation
  • stay on HFOV for at least 4 h
Exclusion Criteria
  • any congenital anomaly
  • HFOV duration less then 4 h

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
DeathHFOVPatients who are treated with HFOV at least for 4 h in case of unresponse to conventional ventilation but died.
SurvivedHFOVPatients who are treated with HFOV at least for 4 h in case of unresponse to conventional ventilation and survived.
Primary Outcome Measures
NameTimeMethod
Survival3 months
Secondary Outcome Measures
NameTimeMethod
Cut-off gestational age for survival3 months
Cut-off birthweight for survival3 months

Trial Locations

Locations (1)

Ankara University Children's Hospital

🇹🇷

Ankara, Turkey

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