The use of high frequency oscillator ventilation (HFOV) in paediatric acute respiratory distress syndrome (ARDS) with open lung technique

Completed

• Conditions: Paediatic acute respiratory distress syndrome (ARDS); Respiratory; Respiratory failure, not elsewhere classified

• Registration Number: ISRCTN19924570
• Lead Sponsor: Rachada Pisek Somphotch (Thailand)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09-07
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Paediatric patients aged greater than 1 month to less than 15 years old (from January 2007 - November 2008), either sex
2. Diagnosis of ARDS within 72 hours of Paediatric Intensive Care Unit (PICU) admission
3. No exclusion criteria

Exclusion Criteria

1. Pulmonary capillary wedge pressure greater than or equal to 18 mmHg
2. Evidence of left atrial hypertension
3. Severe irreversible neurological injury or intractable shock
4. The underlying disease was deemed irreversible or ARDS greater than 48 hours
5. Pre-existing air leak syndrome (e.g., pneumothorax or pneumomediastinum)
6. Pre-existing cystic lung disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oxygenation response, measured at 28 days in PIC

Secondary Outcome Measures

Name	Time	Method
Mortality, measured at 28 days in PIC