Comparison of two modes of ventilation NHFOV( newer entity) and NIPPV( pre existing entity) in premature babies who require respiratory support.
Not Applicable
- Conditions
- Health Condition 1: P229- Respiratory distress of newborn, unspecified
- Registration Number
- CTRI/2023/05/053140
- Lead Sponsor
- Pt.B D Sharma University Health Sciences,
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All inborn preterm neonates from 28 to 34+6 weeks of life requiring respiratory support with Silverman Anderson Score > 3.
Exclusion Criteria
ï?· Neonates who are outborn. ï?· Neonates who need intubation for surfactant administration. ï?· Neonates with significant morbidity apart from RDS including cardiac disease, congenital malformations, upper airway anomalies, suspected metabolic disorders, severe cardiovascular instability. ï?· Neonates who had either respiratory distress secondary to severe asphyxia (Apgar score <= 3 at 1 and 5 minute), severe intraventricular hemorrhage (IVH) on admission. ï?· Neonates whose parents refuse consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome will be the need for invasive mechanical ventilation within the first 72 hours of life and total duration of respiratory support through NHFOV or NIPPV.Timepoint: At 72 hours of life
- Secondary Outcome Measures
Name Time Method The secondary outcomes will be duration of respiratory support <br/ ><br>duration of hospitalization, <br/ ><br>time taken to reach full spoon feeds,incidence of air leaks, grade 3 and 4 IVH, <br/ ><br> BPD, <br/ ><br>traumatization of nasal skin and mucosa, <br/ ><br>rate of feed intolerance.Timepoint: -at the time of Weaning off the respiratory support <br/ ><br>-at the time of discharge <br/ ><br>-at the time of attainment of full spoon feeds. <br/ ><br>-babies will be under continuous monitoring in nicu,events will be registered as soon as they happen.