Medication Regimen Complexity and Glycemic Control in Patients With Diabetes

Not Applicable

Completed

• Conditions: Diabetes Mellitus
• Interventions: Other: Medications review

• Registration Number: NCT03324971
• Lead Sponsor: Kasr El Aini Hospital

Brief Summary

Polypharmacy is an alarming health issue that is defined as prescription of multiple medications, of which some are redundant or unnecessary. Due to comorbidities, diabetic patients are often prescribed multiple medications. Over prescribing occurs either due to, prescribing medications that are not indicated, continuation of certain medications beyond the time of indication, or prescribing more than one medication with the same effect. Improving glycaemic control is the cornerstone for the prevention and treatment of the diabetic complications.

Detailed Description

Hypothesis In addition to the side effects and cost of the unnecessary medications, the investigators hypothesis is that poly-pharmacy will adversely affect patients' compliance with the necessary medications.The investigators propose that elimination of unnecessary medications might improve patients' compliance and consequently improve glycemic control diabetic patients.

Study Timeline

• Study Start: 2017-06-02
• Primary Completion: 2017-10-02
• Study First Submitted: 2017-10-20
• Study First Submitted QC: 2017-10-24
• Study First Posted: 2017-10-30
• Study Completion: 2017-12-07
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-31
• Last Update Posted: 2018-09-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

All diabetic patients who are eligible by fulfilling all of the following criteria:

1. HGBA1c ≥7 mg/dl.
2. 2. Poly-pharmacy: defined as the use of five or more medications.
3. Non- compliance: patients were surveyed with both direct and indirect methods to identify non adherence.

Exclusion Criteria

Exclusion after recruitment Any patient whose diabetic medications regimen changed after recruitment due to hospitalisation, illness, stress or patients preference, will be excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Diabetic patients with non-adherence and poly-pharmacy	Medications review	Medications review. Elimination of all unnecessary prescription to cut down the number of medications to the least possible number.

Primary Outcome Measures

Name	Time	Method
Change in Hemoglobin A1c	3 months	measurement of hemoglobin A1c to determine glycemic control.

Trial Locations

Locations (1)

Cairo university hospitals; 🇪🇬 Cairo, Egypt