Effect of Guava Leaves Extract Mouth Wash on Antibacterial Activity, Salivary pH and Patient Satisfaction Compared to Chlorhexidine Mouth Wash in High Caries Risk Patients: A Randomized Control Clinical Trial
试验速览
- 阶段
- 2 期
- 入组人数
- 94
- 主要终点
- Anti-bacterial effect against streptococcus mutans
研究概览
简要总结
This trial is to test the antibacterial effect of Guava leaves extract mouth wash compared to Chlorhexidine mouth wash in high caries risk patients.
Also salivary pH and patient satisfaction to taste will also be tested.
详细描述
This study is conducted to evaluate the effect of Guava leaves extract mouth wash on anti-bacterial activity against streptococcus mutans, salivary pH and patient satisfaction to taste compared to Chlorhexidine mouth wash.
P: Population with high caries risk patients I: Intervention by Guava leaves extract mouthwash C: Control is Chlorhexidine mouthwash O1: The primary outcome is antibacterial activity. O2: The secondary outcome is salivary pH O3: The tertiary outcome is patient satisfaction to taste
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Guava leaves extract
A natural product that is prepared as a mouthwash
干预措施: Guava leaves extract (Drug)
Chlorhexidine
chemical agent Chlorhexidine as a mouthwash
干预措施: Chlorhexidine (Drug)
结局指标
主要结局
Anti-bacterial effect against streptococcus mutans
时间窗: 3 months
Antimicrobial effect against streptococcus mutans: saliva samples collected and total bacterial count measured after agar plates incubating, expressed in colony forming units
次要结局
- Salivary pH(3 months)
研究者
Engy Mostafa Magdy Abdou Ahmed Kassem
Assistant Lecturer
Cairo University