The Efficacy of permanent sacral nerve Stimulation upon constipation symptoms in patients with severe constipation: A Randomised Controlled trial

Not Applicable

Active, not recruiting

• Conditions: Slow transit constipation; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12611001192976
• Lead Sponsor: Prof Ian COOK MD (SYD) FRACP

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-11-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

Patients must be
Rome II positive for constipation with unsatisfactory response to standard therapies
Slow transit constipation confirmed by scintigraphic or marker study
free of medication which indicates constipation as a side effect
Patients complete a 3week stool diary detailing bowel movements on a daily basis over a 3 week period
Eligiblty is determined on the basis of less than 2 days per week a feeling of incomplete evacuation.
Rome II positive according to survey 'A study of Constipation'
Slow transit constipation with a % retention greater than 9% @ 72 hours
Normal ano rectal manometry

Exclusion Criteria

Prior abdominal surgery(ecept cholecystectomy, appendectomey, hernia repair, splenecomy, fundoplication;oophorectomy or hysterectomy)
Medications which list constipation as a side effect
Other medical complications
non english speaker or an inability to provide informed consent
inability to make fortnightly visits to St George Hospital over a 3 month period

Study & Design

• Study Type: Interventional
• Study Design: Not specified