Prevalence of Cardiac Amyloidosis in Heart Failure Patients With Preserved Left Ventricular Ejection Fraction in Tunisia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 87
- 试验地点
- 2
- 主要终点
- Prevalence of cardiac amyloidosis among HFpEF old Tunisian Patients
研究概览
简要总结
Cardiac amyloidosis (CA) has recently been reported as a common cause of heart failure with preserved left ventricular ejection fraction (HFpEF), with a prevalence of 6% in elderly HFpEF patients. However, the diagnosis of CA is still challenging and requires multiple costly investigations.
Regardless of the type of CA, TTR or AL, early diagnosis significantly improves prognosis.
In this study, the investigators aimed to determine the prevalence of CA in Tunisian HFpEF patients and to identify clinical and ultrasound criteria predictive of CA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •HFpEF during the previous year
- •IVS thickness of 12mm or greater
排除标准
- •age under 60 years
- •Acute coronary syndrome complicated by HFpEF
- •Congenital heart disease
结局指标
主要结局
Prevalence of cardiac amyloidosis among HFpEF old Tunisian Patients
时间窗: one year
Prevalence of cardiac amyloidosis in a Tunisian cohort of HFpEF patients aged 60 years or older with interventricular septal thickness equal to or greater than 12 mm
次要结局
- Frequency of different types of cardiac amyloidosis(one year)
- Identify imaging criteria predictive of cardiac amyloidosis on CMR and echocardiography(one year)
研究者
Lilia Zakhama
Professor
University Tunis El Manar