The Effect of Dietary Approach to Stop Hypertension (DASH) on Insulin Resistance

Not Applicable

• Conditions: healthy obese volunteer.; Simple obesity NOS

• Registration Number: IRCT2014090719072N1
• Lead Sponsor: Isfahan University of Medica Science ,Deputy Director of Research and Development

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Inclusion Criteria: female; Body Mass Index above 30; age 20-50; absence of cardiovascular; hepatic; renal; thyroid; diabetes; rheumatoid arthritis; lupus; severe infection; trauma; allergy disease; don't use of multivitamin and mineral or omega-3 fatty acids supplements; don't regular use of antacid drugs containing magnesium and calcium ; consumption Aspirin and Non Steroid Anti Inflammation; and anti-depressant and hormone drugs; lack of pregnancy and breastfeeding; don't get weight loss in 6 months (more than 1 kg; don't use of tobacco and alcohol.
Exclusion criteria: Failure to follow the prescribed diet( energy intake is different more than 300 calorie from prescribed as regard to food record analysis
), if weight change is more than 5%, diagnosis one of mentioned disease in inclusion criteria and using of chemical or herbal medicines during the study.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PPAR gamma Gene Expression. Timepoint: Before Intervention and After 3 Months. Method of measurement: Real Time Polymerase Chain Reaction.;IRS1 Gene Expression. Timepoint: Before Intervention and After 3 Months. Method of measurement: Real Time Polymerase Chain Reaction.;Insulin resistance. Timepoint: Before Intervention and After 3 Months. Method of measurement: Hemostatic Model Assessment(HOMA).

Secondary Outcome Measures

Name	Time	Method
Weight. Timepoint: Before Study and After 3 Months. Method of measurement: Scale.;Fasting Sugar. Timepoint: Before Study and After 3 Months. Method of measurement: Caloremetric.;Fasting Insulin. Timepoint: Before Study and After 3 Month. Method of measurement: Elisa Method.