octurnal CPAP in Aspiration pneumonia
- Conditions
- Diseases of the respiratory system
- Registration Number
- KCT0003469
- Lead Sponsor
- Seoul National University Bundang Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Terminated
- Sex
- All
- Target Recruitment
- 40
? Age = 65 years
? Diagnosis of pneumonia: the presence of new pulmonary infiltration in dependent areas on chest radiographs at the time of hospitalization with at least one of the following
-New or increased cough
-An abnormal temperature (< 35.6? or > 37.8?)
-An abnormal serum leukocyte count (leukocytosis, left shift, or leukopenia)
? Aspiration tendency or risk factors for frequent or large volume aspiration with at least one of the following
-Altered mental status
-Gastrointestinal disorder
-Dysphagia or swallowing difficulties
-Esophageal motility disorders
-Tracheostomy state
-Enteral tube feeding
? Informed consent
? Severe hypercapnia (PaCO2 > 70mmHg)
? Respiratory arrest requiring tracheal intubation
? Cardiac arrest, acute coronary syndrome or life threatening arrhythmias
? Failure of more than two organs
? Recent trauma or burns of the neck and face
? Non- cooperation
? Pregnancy
? Withdrawal of consent
? Refusal of treatment
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to respiratory clinical stability
- Secondary Outcome Measures
Name Time Method Time to clinical stability;Early clinical stability (day 3) rate;Late clinical stability (day 7) rate;Radiological improvement (day 3, 7);Broadening of antimicrobial spectrum;frequency of suction, bronchoscopy for toileting;Hospital length of stay;In-hospital mortality