Effects of Nasal Continuous Positive Airway Pressure Compared with High Flow Nasal Cannula on The Coordination Between Swallowing and Breathing in Post-extubation Patients, a Randomized Crossover Study
Phase 1
- Conditions
- Swallowing- breathing coordination in postextubation patients using nasal continuous positive airway pressure and high flow nasal cannulanasal continuous positive airway pressurehigh flow nasal cannulaswallowing and breathing coordinationpostextubation patients
- Registration Number
- TCTR20210607003
- Lead Sponsor
- Ratchadapisek Research Funds, Faculty of Medicine, Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 26
Inclusion Criteria
1. intubated for more than 48 hours and extubated within 48 hours
2. able to maintain adequate oxygen saturation by using low flow oxygen cannula 1-5 LPM
3. have stable vital signs
4. pass the modified swallowing test with the score of more than 3 points
Exclusion Criteria
1. not cooperative
2. have contraindication for enteral feeding
3. cerebrovascular disease, neuromuscular disease or muscle weakness
4. head and neck cancer
5. structural abnormalities of oral cavity or pharynx
6. history of surgery within oral cavity or pharyngeal area
7. delirium
8. previous diagnosis of dysphagia
9. skin lesions which interfered with EMG monitoring
10. have automated implantable cardioverter-defibrillator or permanent pacemaker
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The frequency of each pattern of the timing of swallowing in relation to respiratory phases about 5 minutes while using the devices (HFNC and CPAP) The swallowing was recorded by surface electromyography (EMG) of swallowing muscles and respiratory phases were monitored by ECG-derived respiratory signals and surface EMG of respiratory muscles.
- Secondary Outcome Measures
Name Time Method Factors affect swallowing-breathing coordination during the experiment Clinical data and baseline charachteristic of participants will be collected from electronic medical record