Effects of Continuous Airway Pressure on the ability to heat and humidify air in healthy subjects.

• Conditions: Healthy subjects; Respiratory - Normal development and function of the respiratory system

• Registration Number: ACTRN12605000797673
• Lead Sponsor: Fisher and Paykel Healthcare

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-12-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

A clinical history suggestive of normal nose and upper airway, other than during a cold.Willingness of the subject to participate in and complete the study, and the ability to understand the purpose of the trial.

Exclusion Criteria

Physical sign or symptoms suggestive of renal, hepatic or cardiovascular disease.Women of childbearing potential who are pregnant, trying to become pregnant or nursing a child.Subjects treated with systemic steroids during the previous 30 days.Subjects treated with topical (inhaled, intranasal or intraocular) steroids, Nasalcrom or Opticrom during the previous 15 days.Subjects treated with oral antihistamine/decongestants during the previous seven days.Subjects treated with topical (intranasal or intraocular) antihistamine/decongestants during the previous 3 days.Subjects treated with immunotherapy.Subjects on chronic anti-asthma medications.Subjects with polyps in the nose or a significantly displaced septum.Subjects who have incurred an upper respiratory tract infection within 14 days of the start of the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
asal Mucosal Temperature[Measured after each 12-minute pressure application.]

Secondary Outcome Measures

Name	Time	Method
Airway geometry[Measured after each 12-minute pressure application.]