The effects of continuous positive airway pressure (CPAP) treatment on brain activity during sleep in obstructive sleep apnea (OSA).

Not Applicable

Completed

• Conditions: obstructive sleep apnea; sleep disorders; Respiratory - Sleep apnoea; Neurological - Studies of the normal brain and nervous system

• Registration Number: ACTRN12617000336381
• Lead Sponsor: Woolcock Institute of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-03
• Study Completion: 2018-08-23
• Last Update Posted: 15 August 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 15

Inclusion Criteria

A diagnosis of moderate OSA defined by an apnea-hypopnea index (AHI) of greater than 15/hr as measured by PSG and confirmed by sleep physician. Participants must be recommended for CPAP treatment by their treating physician and be willing to commence 3 months of CPAP use. Participants must fluent in English and also have the ability to perform neurobehavioural tests and provide informed consent.

Exclusion Criteria

Clinically significant co-morbidity; history of head injury or psychiatric/neurological disorder (including stroke); use of CNS active agents; heavy alcohol consumption (40g daily); current shift-worker or travelled overseas within the last 2 weeks; previously used CPAP.

Study & Design

• Study Type: Observational
• Study Design: Not specified