The impact of continuous positive airway pressure (CPAP) on aortic aneurysms in patients with obstructive sleep apnea
Not Applicable
- Conditions
- obstructive sleep apnea aortic aneurysm
- Registration Number
- JPRN-UMIN000011592
- Lead Sponsor
- Graduate School of Medicine, Kyoto University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Not provided
Exclusion Criteria
1. Previous or current treatments for sleep apnea. 2. Previous treatment for aortic aneurysm 3. Planned intervention for aortic aneurysm 4. Central sleep apnea syndrome 5. Long-term oxygen therapy 6. Aortic aneurysm associated with hereditary diseases (e.g. Marfan syndrome) 7. Unable to use CPAP 8. Hope for treatments other than CPAP for OSA 9. Surgery of upper airway within 90 days
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The changes in the expansion rate of aortic aneurysms (mm/year) before and after the CPAP treatment
- Secondary Outcome Measures
Name Time Method 1. Expansion rate (mm/year) of aortic aneurysms in patients without CPAP treatment 2. Prevalence of OSA in patients with aortic aneurysm 3. Events associated with aortic aneurysm 4. Cardiovascular events 5. Changes in biomarkers of aortic aneurysm 6. Changes in blood pressure and endothelial function 7. Changes in epicardial fat and visceral fat volume 8. Changes in sleep duration