A study to compare the effects of ondansetron and glycopyrrolate to prevent the fall in blood pressure and heart rate following spinal anaesthesia in patients undergoing lower limb orthopaedic surgery

Phase 3

• Conditions: Health Condition 1: M844- Pathological fracture, not elsewhere classifiedHealth Condition 2: M844- Pathological fracture, not elsewhere classified

• Registration Number: CTRI/2022/05/042507
• Lead Sponsor: Caicutta National Medical College And Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 May 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients of age 18-45 years, either sex, ASA physical status I & II undergoing elective lower limb orthopaedic surgeries under spinal anaesthesia will be included in this

study.

Exclusion Criteria

(i) Patients having contraindications for spinal anaesthesia like lack of consent, raised intra cranial tension, infection at local site, severe aortic stenosis, coagulopathy, cardiovascular instability.

(ii) Patients with known allergy to study drugs

(iii) Patients with BMI > 30 kg/m²

(iv) Patients having height < 150 cm

(v) Patients ASA physical status III or more

(vi) Patients having major cardiovascular,

respiratory, renal, hepatic, metabolic, neurological or endocrine diseases.

(vii) Patients with glaucoma

(viii) Patients receiving any antihypertensive, vasodilator, antiarrhythmic or antiemetic

agents

(ix) Patients requiring general anaesthesia

Study & Design

• Study Type: Interventional
• Study Design: Not specified