The effects of ondansetron, dexamethasone and the combination of these two drugs in reducing nausea and vomiting in childre
Phase 3
- Conditions
- nausea and vomiting.Nausea and vomiting
- Registration Number
- IRCT20160307026950N7
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 144
Inclusion Criteria
Children aged 1 to 12 years old
ASA I and II
candidates for upper gastrointestinal tract endoscopy
parental consent for participation in the study
Exclusion Criteria
History of allergy to study drug
Severe respiratory disease
Severe cardiovascular disease
uncontrolled diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Heart rate. Timepoint: Before the intervention (0), then every 5 minutes until the end of endoscopy and then every 15 minutes until discharge the recovery. Method of measurement: Pulse oximetry device.;Nausea and vomiting. Timepoint: Every 15 minutes in recovery room, and then 2, 4 and 6 hours after endoscopy. Method of measurement: Baxter Retching Face Nausea Scale.;Mean arterial blood pressure. Timepoint: Before the intervention (0), then every 5 minutes until the end of endoscopy and then every 15 minutes until discharge the recovery. Method of measurement: non invasive blood pressure sphygmomanometer.;Arterial oxygen saturation. Timepoint: Before the intervention (0), then every 5 minutes until the end of endoscopy and then every 15 minutes until discharge the recovery. Method of measurement: Pulse oximetry device.
- Secondary Outcome Measures
Name Time Method Duration of stay in recovery. Timepoint: From recovery admission to recovery discharge. Method of measurement: Watch or clock.