The transition from acute to chronic post-surgical pain - a prospective, randomised controlled trial of two medications (nortriptyline and gabapentin) in 150 participants undergoing hip or knee replacement surgery.
Phase 4
- Conditions
- Anaesthesiology - Pain managementThe transition between acute and chronic post-surgical pain
- Registration Number
- ACTRN12614000379617
- Lead Sponsor
- niversity of Otago, Christchurch
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
17 years of age and over undergoing surgery for hip and knee arthroplasty at Burwood Public Hospital
Exclusion Criteria
Those under 17 years of age
Those with cognitive impairments
Those currently receiving treatment with secondary analgesics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Presence or absence of chronic pain, as determined by a pain score equal to or greater than 4 (out of 10) on a visual analogue scale.[Three (3) months post-operatively]
- Secondary Outcome Measures
Name Time Method Predicting pain post operatively in the group receiving routine management. This will, as above, be measured by the visual analogue scale, and the potentially predictive tools will be the psychometric questionnaires, and the cold pressor test.<br> [Three (3) months post operatively];Predicting post operative pain from baseline data, which will be collected by the multiple psychometric questionnaires conducted at baseline, the results of the cold pressor test, as well as the participants' relevant medical records. This will be tested by the same visual analogue scoring system as above,[Six (6) weeks post operatively]