Evaluation of bupivacaine induced myotoxicity after giving ultrasound guided erector spinae block in patients undergoing modified radical mastectomy by measuring pre op and post op serum CPK levels
Phase 3
Completed
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified siteHealth Condition 2: C509- Malignant neoplasm of breast of unspecified site
- Registration Number
- CTRI/2023/02/050113
- Lead Sponsor
- Pt B D Sharma PGIMS ROHTAK MR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Female patients aged 20-60 years with American Society of Anesthesiologists- physical status I
and II, scheduled to undergo MRM for carcinoma breast under general anaesthesia (GA)
Exclusion Criteria
1. Not willing to give consent
2. With infection at the needle insertion site
3. With known hypersensitivity to local anaesthetic agent
4. With bleeding disorder or on anticoagulant
5. With BMI > 30 kg/m²
6. With musculoskeletal disorder
7. With chest wall deformity
8. With pregnancy or lactation
9. With difficult airway
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To measure serum CPK levels postoperatively in ultrasound guided erector <br/ ><br>spinae block in patients undergoing MRMTimepoint: To measure serum baseline CPK levels,at 6 hours ,at 24 hours postoperatively in ultrasound guided erector <br/ ><br>spinae block in patients undergoing MRM
- Secondary Outcome Measures
Name Time Method <br/ ><br>1. Intra operative fentanyl consumption <br/ ><br>2. Post operative pain score <br/ ><br>3. Time for requirement of first rescue analgesia <br/ ><br>4. Analgesic consumption in 24 hoursTimepoint: Pain assessment will be done post operatively using VAS at <br/ ><br>0,1,6,12,18,24th hour after surgery.