Determination of effective drug in prevention of post spinal hypotension in C/S
Phase 2
Recruiting
- Conditions
- post spinal anaesthesia hypotension.Other complications of spinal and epidural anaesthesia during labour and delivery
- Registration Number
- IRCT20120915010841N8
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
ASA CLASS 1(Healthy Patients)
18-45 aged pregnant patients for C/S
Exclusion Criteria
Cardiac disease
Renal disease
History of hypertensive disease
Diabetes
Eclampsia ⪯ eclampsia
Multiple pregnancy
C/S for meconium or fetal distress
Contraindications for spinal anesthesia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic blood pressure. Timepoint: Minutes of 0,2, 4, 6, 8, 10,15, 20, 25, 30, 40, 50 and 60 after spinal anesthesia. Method of measurement: Automatic non-invasive blood pressure device.;Diastolic blood pressure. Timepoint: Minutes of 0,2, 4, 6, 8, 10,15, 20, 25, 30, 40, 50 and 60 after spinal anesthesia. Method of measurement: Automatic non-invasive blood pressure device.;Mean arterial pressure. Timepoint: Minutes of 0,2, 4, 6, 8, 10,15, 20, 25, 30, 40, 50 and 60 after spinal anesthesia. Method of measurement: Automatic non-invasive blood pressure device.
- Secondary Outcome Measures
Name Time Method Heart rate. Timepoint: Minutes of 0,2, 4, 6, 8, 10,15, 20, 25, 30, 40, 50 and 60 after spinal anesthesia. Method of measurement: Pulse oximetry device.;Arterial oxygen saturation. Timepoint: Minutes of 0,2, 4, 6, 8, 10,15, 20, 25, 30, 40, 50 and 60 after spinal anesthesia. Method of measurement: Pulse oximetry device.;Nausea and vomiting. Timepoint: During surgery. Method of measurement: Observation.;Apgar Score of neonate. Timepoint: The first and fifth minutes after birth. Method of measurement: Examination and calculation on Apgar score.;The amount of ephedrine have been consumed. Timepoint: during surgery. Method of measurement: The amount of ephedrine have been consumed by mg.;The amount of atropine have been consumed. Timepoint: during surgery. Method of measurement: The amount of atropine have been consumed by mg.