Comparison of Intravenous Phenylephrine and Ephedrine to Treat Hypotension Associated with Spinal Anesthesia in Patients Undergoing Cesarean Sectio
- Conditions
- Maternal hypotension.Maternal hypotension syndrome
- Registration Number
- IRCT2015050622131N1
- Lead Sponsor
- Vice Chancellor Of Research Zahedan University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 120
Pregnant women 2o-35 years old ;Elective cesarean;ASA1; Singleton pregnancy;36 to 40 weeks gestational age;Weighing 45 to 90 kg;145 to 180 cm height;Informed consent for inclusion Exclusion criteria beginning: History of Primary hypertension (Bp=140/90);cardio-cerebrovascular diseases; Diabetic mellitus;Sensitivity to anesthetics;Pregnancy complications such as gestational hypertension;Placental abnormalities;Umbilical cord abnormalities;High-risk pregnancies(Multiple pregnancy?Intrauterine growth retardation);Spinal anesthesia ban(Prevention of spinal anesthesia?Coagulation disorder?Infection of spinal anesthesia area);Lack of consent to participate in the study
Exclusion criteria during the study:Unpredictable events during surgery
such as abnormal hemorrhage under surgery; unsuccessful spinal anesthesia;high spinal Anesthesia (at level above T4); more than 75min surgery duration
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure. Timepoint: After spinal anesthesia,75 minutes (every 3 minutes for the first 15-minute period and every 10 minutes for the following 60-minute period. Method of measurement: mmHg by SIEMENS SC 7000 monitoring system.;Heart rate. Timepoint: After spinal anesthesia, were checked for 75 minutes (every 3 minutes for the first 15-minute period and every 10 minutes for the following 60-minute period. Method of measurement: Number by SIEMENS SC 7000 Monitoring system.
- Secondary Outcome Measures
Name Time Method Base Exess. Timepoint: After the extraction of fetus and umbilical cord clamp. Method of measurement: Number -Based on the arterial umbilical cord Base Exess,that was measured by blood gas analyzer ,GASTAT-603ie.;Nausea. Timepoint: During Surgery. Method of measurement: Has/has not,Patient-reported.;Vomiting. Timepoint: During Surgery. Method of measurement: Has/has not,Observer-reported.;Umbilical cord Ph. Timepoint: After the extraction of fetus and umbilical cord clamp. Method of measurement: Number -Based on the arterial umbilical cord PH,that was measured by blood gas analyzer ,GASTAT-603ie.;Neonatal Apgar. Timepoint: At 1 and 5 minutes after birth. Method of measurement: Based on clinical examination.