NCT01594034已完成不适用
Effects of Hemoperitoneum Driven Carbon Monoxide on Post-Traumatic Stability
The University of Texas Health Science Center at San Antonio1 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2009年11月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- •Establish a method for reliably measuring CO excretion in patients.
研究概览
简要总结
Our objective is to determine whether or not the presence of hemoperitoneum in trauma patients is associated with increased Carbon Monoxide (CO) formation, and to determine if elevated Carbon Monoxide levels are associated with cardiovascular depression, impaired platelet aggregation, and/or multiple organ failure.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Hospitalized males 18 years of age or older,
- •Diagnosis of isolated blunt OR blunt and penetrating trauma,
- •Admitted or expecting to be admitted to the Intensive Care Unit,
- •On mechanical ventilation, and
- •Written informed consent obtained
排除标准
- •Female gender, (Females will be excluded from this study as the menstrual cycle and other estrogen variations are known to be associated with cyclic changes in CO production adding a potential confounder to the interpretations of our findings.)
- •Diagnosis of isolated penetrating trauma,
- •Acute hemothorax or pneumothorax,
- •Treatment with antiaggregants (ASA, clopidogrel, aggrenox or ticlopidine),
- •Enrollment in another research study,
- •Inability to perform CO measurement within 96 hours after hospital admission.
结局指标
主要结局
•Establish a method for reliably measuring CO excretion in patients.
时间窗: 96 hours
次要结局
未报告次要终点
研究者
研究点 (1)
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