Improving Cognitive Function in Chinese Children With ADHD and/or RD Through Computerized Working Memory Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 122
- 试验地点
- 1
- 主要终点
- Intellectual ability
研究概览
简要总结
Prior research has found that children with attention-deficit hyperactivity disorder (ADHD) and reading difficulties (RD) are at an elevated risk of developing further cognitive deficits and developmental challenges. ADHD and RD are characterized by a deficit in working memory, which negatively affects learning and behavior. The main aims of this study were to design a working memory training app and examine its effectiveness through a 5-week training program in Chinese children with ADHD and/or RD. There were three experimental groups, with 26 participants in the ADHD group, 38 participants in the RD group, and 24 participants in the ADHD+RD group. The typically developing (TD) control group had 32 participants. All participants completed the pretest and posttest assessments on executive function and reading performance.
详细描述
Attention-deficit hyperactivity disorder (ADHD) is marked by attention issues and hyperactive-impulsive behaviors. It affects about 7.2% of school-aged children globally, with a 6.5% prevalence in Hong Kong. Reading difficulties (RD) involve persistent challenges in reading and writing, unrelated to brain damage, sensory impairments, or low intelligence. ADHD and RD often co-occur, with a comorbidity rate of 25%-40%, surpassing chance probabilities.
Research indicates that children facing the dual challenge of ADHD and RD are more vulnerable to significant cognitive deficits, particularly in working memory. This vital cognitive function strongly influences academic abilities like math problem-solving, reading, and language understanding. Deficiencies in working memory can result in learning overwhelm, memory lapses with instructions, and struggles with complex tasks in children. Consequently, individuals with this comorbidity are predisposed to more challenges compared to those with a singular disorder.
Studies have verified that individuals with both ADHD and RD symptoms face increased chances of school abandonment, disruptive conduct, delinquency, and notably, more aggression compared to those with singular conditions. These results emphasize the need for additional research to develop a fresh intervention strategy targeting this comorbid cohort, aiming to pre-empt these adverse consequences. The subsequent sections will provide a concise overview of the theoretical basis of working memory and its ties to ADHD and RD, followed by the development of a working memory training application and the research methodology.
Working memory, a crucial cognitive function, involves temporarily storing, processing, and recalling information within specific limits. It underpins various mental processes like problem-solving, language comprehension, and fluid intelligence. This ability is vital for learning new concepts and skills, correlating strongly with vocabulary growth, language understanding, and reading ability. Baddeley and Hitch's influential working memory model includes a central executive, the phonological loop, the visuospatial sketchpad, and later, the episodic buffer. The central executive plays a pivotal role in coordinating these components, managing data retrieval and manipulation while allocating resources to the storage systems.
The phonological loop specializes in processing language-related data crucial for language learning. Meanwhile, the visuospatial sketchpad handles visual and spatial information, linked to nonverbal intelligence and orthographic awareness. The episodic buffer acts as a unified episodic representation, capable of integrating data from other components and long-term memory. This model illuminates how working memory functions, influences cognitive processes, and develops over time.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 6 Years 至 11 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •being aged between 6 and 11
- •having an intelligence quotient (IQ) score above 80
- •having a clinical diagnosis of ADHD and/or RD from a clinical or educational psychologist or a psychiatrist
- •speaking native Cantonese
排除标准
- •brain damage, neurological issues, sensory problems, or psychiatric issues
结局指标
主要结局
Intellectual ability
时间窗: Two weeks before the pretest
The Raven's Progressive Matrices comprises five sets (starting with set A and ending with set E) of 12 items each, totalling 60 items. Each presents a visual pattern with a missing piece. Participants were required to identify the missing piece that would complete the pattern.
Central executive function
时间窗: One week after the intervention
The central executive function subscale of BRIEF consists of 10 items. Teachers rated their student's behavior using a 3-point Likert scale (1 = never, 2 = sometimes; 3 = often). All 10 items were added together to form the central executive function subscale.
Verbal working memory
时间窗: One week after the intervention
Verbal working memory capacity was measured using the third edition of the backward digit spans subtest from the Wechsler Intelligence Scale for Children (WISC-III). Participants were presented with two to nine orally delivered digits and asked to recall them in reverse order. They must retain auditory information while filtering out irrelevant details and focusing on relevant ones. The backward digit spans subtest consists of 18 trials, and participants who correctly repeated the backward digit sequence received one point.
Visual-spatial working memory
时间窗: One week after the intervention
Visual-spatial working memory was assessed using the Spatial Working Memory Test (SWM) from Cambridge Cognition. This computerized measure presents several boxes on the screen. Participants were asked to locate a hidden yellow token in each search. Once the token is collected, participants must continue searching for the remaining tokens until all of them have been found (the number of tokens equals the number of boxes). The token never appears in boxes where one has been found before. The number of boxes increases in difficulty from four to eight.
Chinese word reading
时间窗: One week after the intervention
The 1-minute word reading test from HKT-P(III) was used to measure reading fluency. It consists of 120 simple Chinese two-character words. Participants were asked to read the words as quickly and accurately as possible within a minute. The total number of words read correctly was recorded, and the reading ability score can vary between 0 and 120.
次要结局
未报告次要终点
