The Effects of Working Memory Training in Children With Attention-Deficit/Hyperactivity Disorder

Not Applicable

Completed

• Conditions: Attention Deficit Disorder With Hyperactivity; Psychophysiology
• Interventions: Other: Working memory training; Other: perceptual training

• Registration Number: NCT02959528
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

Previous studies indicated that children with attention-deficit/hyperactivity disorder (ADHD) often suffer from deficits in executive function, such as attentional control, inhibition, and working memory. One of these executive functions, working memory, plays a critical role in academic performance and classroom behavior. Working memory is essential for performing complex cognitive tasks such as comprehension, learning, and reasoning. Several studies have shown that training of working memory has positive effects for ADHD and other cognitive disorder in children. However, transfer effects across studies appear to be variable and inconsistent. Event-related potentials can be a useful tool to gain insights into such mechanism. Therefore, the aim of the present study is to investigate both near and far transfer effects of N-back training in children with ADHD. In addition, the recording and analysis of event-related potentials will be adopted while children with ADHD perform the complex visuo-spatial and phonological working memory tasks.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-10
• Study First Submitted: 2016-10-31
• Study First Submitted QC: 2016-11-07
• Study First Posted: 2016-11-09
• Primary Completion: 2016-11-25
• Study Completion: 2017-01-19
• Status Verified: 2017-10
• Last Update Submitted: 2017-10-25
• Last Update Posted: 2017-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• ADHD diagnosed according to criteria specified in Diagnostic and statistical manual of mental disorders (DSM-5)
• aged between 8 and 10 years
• intelligence quotient > 80 (based on Test of Nonverbal Intelligence-Third Edition)
• had normal or corrected-to-normal vision
• right-handed

Exclusion Criteria

• diagnosis of clinically significant oppositional defiant disorder, Autistic Spectrum Disorders, Asperger's syndrome or depression
• history of seizures

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experiment	Working memory training	ADHD group treated with working memory training
Control	perceptual training	ADHD group treated with visual-perceptual training

Primary Outcome Measures

Name	Time	Method
Automated Working Memory Assessment	6 weeks	Visuospatial working memory change after intervention measured by Automated Working Memory Assessment

Secondary Outcome Measures

Name	Time	Method
Working memory index in Wechsler Intelligence Scale for Children-IV	6 weeks	Verbal working memory change after intervention measured by Working memory index in WISC-IV
Event-related potentials	6 weeks	Event-related potentials are measured brain response on effects of working memory training

Trial Locations

Locations (1)

Chang Gung University; 🇨🇳 Taoyuan City, Taiwan