The Effects of Working Memory Training in Children With Attention-Deficit/Hyperactivity Disorder
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Attention Deficit Disorder With Hyperactivity
- Sponsor
- Chang Gung Memorial Hospital
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Automated Working Memory Assessment
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Previous studies indicated that children with attention-deficit/hyperactivity disorder (ADHD) often suffer from deficits in executive function, such as attentional control, inhibition, and working memory. One of these executive functions, working memory, plays a critical role in academic performance and classroom behavior. Working memory is essential for performing complex cognitive tasks such as comprehension, learning, and reasoning. Several studies have shown that training of working memory has positive effects for ADHD and other cognitive disorder in children. However, transfer effects across studies appear to be variable and inconsistent. Event-related potentials can be a useful tool to gain insights into such mechanism. Therefore, the aim of the present study is to investigate both near and far transfer effects of N-back training in children with ADHD. In addition, the recording and analysis of event-related potentials will be adopted while children with ADHD perform the complex visuo-spatial and phonological working memory tasks.
Investigators
I-hsuan Shen
Associated professor
Chang Gung Memorial Hospital
Eligibility Criteria
Inclusion Criteria
- •ADHD diagnosed according to criteria specified in Diagnostic and statistical manual of mental disorders (DSM-5)
- •aged between 8 and 10 years
- •intelligence quotient \> 80 (based on Test of Nonverbal Intelligence-Third Edition)
- •had normal or corrected-to-normal vision
- •right-handed
Exclusion Criteria
- •diagnosis of clinically significant oppositional defiant disorder, Autistic Spectrum Disorders, Asperger's syndrome or depression
- •history of seizures
Outcomes
Primary Outcomes
Automated Working Memory Assessment
Time Frame: 6 weeks
Visuospatial working memory change after intervention measured by Automated Working Memory Assessment
Secondary Outcomes
- Working memory index in Wechsler Intelligence Scale for Children-IV(6 weeks)
- Event-related potentials(6 weeks)