DEmEntia with Lewy bOdies Project (DEvELOP)
Recruiting
- Conditions
- Dementia with Lewy bodies (DLB)
- Registration Number
- NL-OMON27253
- Lead Sponsor
- VU Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•Signed informed consent
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded from participation in this study:
•Severe physical or life-threating conditions
Study & Design
- Study Type
- Not specified
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical parameters (cross-sectional and longitudinal)<br /><br>•Cognitive functioning on neuropsychological testing <br /><br>•DLB features <br /><br>•Daily functioning<br /><br /><br><br>•AD pathology as assessed by AD proteins (Aâ42, t-tau and p-tau) in CSF.<br /><br>•Brain atrophy on MRI <br /><br>•EEG abnormalities
- Secondary Outcome Measures
Name Time Method •Response to symptomatic therapy (cholinesterase inhibitors)<br /><br>Biomarker parameters (cross-sectional and longitudinal)