Comparing difficult airway predictors for intubation difficulty: Diabetic versus Non-Diabetic Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- To find out the single best clinical
研究概览
简要总结
This prospective hospital based comparative study will be conducted in the Department of Anaesthesia Mahatma Gandhi Medical College and Hospital Jaipur after ethical committee approval Informed written consent will be obtained from all patients
Patients will be allocated into two groups of one hundred each based on diabetic and non diabetic status
Group D Diabetic patients n equals one hundred
Group ND Non diabetic patients n equals one hundred
On the day before surgery the patient will be examined in the sitting position and the following indices will be assessed
Body mass index
Inter incisor distance
Neck extension
Neck circumference
Mallampati score
Thyromental distance and sternomental distance
upper lip bite test
Prayer sign
Palm print sign
On the day of surgery doses of anti diabetic agents will be withheld Six hours of fasting will be ensured Morning fasting blood sugar will be measured and an intravenous line will be secured
In the operation theater adequate intravenous access will be confirmed Standard monitoring will be attached Non invasive blood pressure pulse oximetry electrocardiogram and end tidal carbon dioxide will be monitored after intubation
Before induction of anesthesia all patients will receive intravenous glycopyrrolate zero point two milligrams intravenous midazolam one milligram and intravenous fentanyl two micrograms per kilogram Anesthesia will be induced with intravenous propofol one point five to two milligrams per kilogram followed by intravenous atracurium zero point five milligrams per kilogram
Laryngoscopy will be performed after three minutes with the patient head in morning air sniffing position using a standard appropriate sized Macintosh blade
The laryngeal view will be graded according to the Cormack and Lehane classification
The patient trachea will be intubated with an appropriate size endotracheal tube and correct placement of the tube will be confirmed by capnography and chest auscultation
In case of difficulty maneuvers and adjuncts such as external laryngeal manipulation change in head position use of different size or type of laryngoscope blade and intubating bougie will be employed
The outcome measure will be the Cormack and Lehane grading of laryngoscopy
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of age 18-70 years Patients of all genders Patients posted for surgery under general anaesthesia requiring endotracheal intubation.
- •ASA Grade 1/2/3.
排除标准
- •Patients with the previous history of difficult intubation Obvious anatomical deformity (congenital, traumatic, post surgical origin) of face, neck, palate and hands.
- •Coexisting factors like rheumatoid arthritis, large thyroid, airway trauma.
- •Emergency surgeries.
- •Pregnant & lactating females.
结局指标
主要结局
To find out the single best clinical
时间窗: 30 minutes after induction of general anaesthesia
parameter of airway assessment and its ability to predict
时间窗: 30 minutes after induction of general anaesthesia
difficult intubation (measured by CL grading) in patients with
时间窗: 30 minutes after induction of general anaesthesia
diabetes mellitus (DM).
时间窗: 30 minutes after induction of general anaesthesia
次要结局
- To find out if prolonged diabetes more than 10(years correlates with increased difficulty in intubation)
研究者
Dr Vadher raj bharatbhai
Mahatma gandhi medical college and hospital