The Diagnostic Utility of Ultrasound in Pelvic Inflammatory Disease (PID)

Active, not recruiting

• Conditions: Pelvic Inflammatory Disease

• Registration Number: NCT06756568
• Lead Sponsor: Superior University

Brief Summary

Pelvic inflammatory disease (PID) represents a significant and complex health issue affecting women, particularly those of reproductive age. Characterized by the infection and inflammation of the reproductive organs, PID often results from ascending infections primarily caused by sexually transmitted pathogens, such as Neisseria gonorrhoeae and Chlamydia trachomation. However, it can also be associated with endogenous bacteria or occur following surgical procedures.

Detailed Description

The diverse manifestations of PID from asymptomatic cases to acute presentations, pose significant challenges in diagnosis and prompt treatment. Accurate diagnosis is crucial, as untreated infections can lead to severe complications, including infertility, chronic pelvic pain, and ectopic pregnancies.

Study Timeline

• Study Start: 2024-02-18
• Primary Completion: 2024-07-01
• Status Verified: 2024-12
• Study First Submitted: 2024-12-26
• Study First Submitted QC: 2024-12-26
• Last Update Submitted: 2024-12-26
• Study First Posted: 2025-01-03
• Last Update Posted: 2025-01-03
• Study Completion: 2025-02-16

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Female
• Target Recruitment: 139

Inclusion Criteria

• Women of reproductive age (18-45 years) presenting with symptoms suggestive of pelvic inflammatory disease (PID).
• Patients who have been clinically diagnosed with PID based on symptoms such as lower abdominal pain, fever, abnormal vaginal discharge, and tenderness upon pelvic examination.
• Patients who have undergone preliminary diagnostic tests, such as high vaginal swab (HVS) and urine microscopy, culture, and sensitivity (m/c/s), prior to ultrasound assessment.

Exclusion Criteria

• Pregnant women, due to potential confounding factors in ultrasound findings and differential diagnosis.
• Patients with chronic pelvic pain not related to acute PID episodes.
• Patients who do not provide informed consent for participation in the study.
• Patients with a history of recent pelvic surgery within the last 6 months, as postoperative changes may affect ultrasound findings.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ultrasound	12 Months	Ultrasound (GE Logiq P7 convex probe.3.5-5MHz) imaging using a curvilinear transducer that provides a broad field of view, commonly used for evaluating abdominal and pelvic organs.; Doppler flow characteristics which increased blood flow in the pelvic region, especially around the fallopian tubes or ovaries, as detected by color Doppler ultrasound, indicative of inflammation.

Trial Locations

Locations (1)

Lady Reading Hospital; 🇵🇰 Peshawar, Khyber Pakhtunkhwa, Pakistan