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A prospective Randomised Controlled Trial assessing recombinant Luteinising Hormone supplementation in patients with a relative reduction in Luteinising Hormone (LH) levels during Vitro Fertilisation/Intracytoplasmic sperm Injection (IVF/ICSI) treatment.

Phase 1
Recruiting
Conditions
Infertility treated with IVF
Low serum LH levels during IVF treatment cycles.
Reproductive Health and Childbirth - Fertility including in vitro fertilisation
Registration Number
ACTRN12610000064000
Lead Sponsor
IVFAustralia
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
697
Inclusion Criteria

1) IVF/ICSI using long pituitary down regulation.
2) No more than 3 stimulated IVF/ICSI treatment cycles before.
3) Not reached 42nd birthday.
4) Consent to undergo study.
5) Regular menstrual cycle.

Exclusion Criteria

1) Oocyte donors.
2) Failure to achieve down regulation within 6 weeks of starting gonadotrophin releasing hormone agonist (GnRH a), are to be excluded for the study.
3) Patients who have already taken part in the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clinical Pregnancy Rate[at about 6 to 8 weeks gestation. defined as a fetal geart beat on ultrasound.]
Secondary Outcome Measures
NameTimeMethod
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