CTRI/2024/01/061575
Not yet recruiting
Phase 2/3
A Prospective Randomized Comparative study of the effect of intravenous Lidocaine versus Dexamethasone on Propofol injection pain
Department of Anaesthesiology1 site in 1 country66 target enrollmentStarted: January 28, 2024Last updated:
Overview
- Phase
- Phase 2/3
- Status
- Not yet recruiting
- Sponsor
- Department of Anaesthesiology
- Enrollment
- 66
- Locations
- 1
- Primary Endpoint
- Verbal Numerical Rating scale
Overview
Brief Summary
This study is a prospective randomized double blind control study to compare the effect of intravenous Lidocaine 40mg or intravenous Dexamethasone 8mg in reducing the pain on injection of Propofol in patients undergoing elective surgeries under General Anaesthesia in KR Hospital
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ALL ASA Grade I AND II patients undergoing elective Surgeries under General Anaesthesia.
Exclusion Criteria
- •All ASA grade III and IV patients Cardiovascular, respiratory and neurological disorders Patients allergic to Propofol and study drugs(soya bean oil,MCT,glycerol,egg lecithin and sodium oleate) Patients in whom hand or forearm veins not accessible Patients having problems in communication.
Outcomes
Primary Outcomes
Verbal Numerical Rating scale
Time Frame: assessed 50 seconds after intravenous injection of Propofol
Secondary Outcomes
- Mc Crirrick & Hunter pain intensity scale(After 50 seconds of intravenous injection of Propofol before patient loses consciousness)
Investigators
Aparna P
Mysore Medical College and Research Institute
Study Sites (1)
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