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A Study of SA-001 to Treat Pancreatic Exocrine Insufficiency

Phase 3
Completed
Conditions
Exocrine Pancreatic Insufficiency, Chronic Pancreatitis
Interventions
Drug: Placebo
Registration Number
NCT00400842
Lead Sponsor
Abbott
Brief Summary

This study is to verify the efficacy of 3.0 g/day of SA-001 in patients with pancreatic exocrine insufficiency caused by chronic pancreatitis in the non-compensatory stage or by pancreatectomy as compared with placebo under a double-blind design using the change in a coefficient of fat absorption as a primary endpoint.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
274
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
LSA-001-
PPlacebo-
HSA-001-
Primary Outcome Measures
NameTimeMethod
Change in CFA from baseline to the end of double-blind treatment7 days after baseline
Secondary Outcome Measures
NameTimeMethod
Stool fat excretion, stool weight, stool frequency, nutritional parameters7 days after baseline

Trial Locations

Locations (98)

Site Reference ID/Investigator# 59845

🇯🇵

Aichi, Japan

Site Reference ID/Investigator# 59933

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Aichi, Japan

Site Reference ID/Investigator# 59928

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Akita, Japan

Site Reference ID/Investigator# 59983

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Amori, Japan

Site Reference ID/Investigator# 59984

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Amori, Japan

Site Reference ID/Investigator# 59569

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Ehime, Japan

Site Reference ID/Investigator# 59938

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Ehime, Japan

Site Reference ID/Investigator# 59571

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Fukuoka, Japan

Site Reference ID/Investigator# 59572

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Fukuoka, Japan

Site Reference ID/Investigator# 59812

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Fukuoka, Japan

Scroll for more (88 remaining)
Site Reference ID/Investigator# 59845
🇯🇵Aichi, Japan

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