The effect of giving tablet Tizanidine before surgery on pain level after surgery in patients undergoing breast surgery.
Phase 4
Not yet recruiting
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/05/067368
- Lead Sponsor
- Dr R Anuradha
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of ASA grade 1 and 2
Patients scheduled for carcinoma breast surgeries
Exclusion Criteria
History of moderate to severe congenital heart disease, neurological disorder, hepatic or renal diseases
Patients with hiatal hernia, major abdominal or thoracic surgery
Patients with history of alpha 2 agonist in last few days to months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative pain score and requirement of rescue analgesia.Timepoint: 0 minute, 30 minutes, 60 minutes, 90 minutes, 2 hours, 3 hours, 4 hours,6 hours,12 hours, 24 hours.
- Secondary Outcome Measures
Name Time Method ength of PACU stay, patient satisfaction and any adverse eventsTimepoint: 24 hours
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms of Tizanidine's alpha-2 adrenergic agonism influence postoperative pain modulation in breast surgery?
How does preoperative Tizanidine compare to midazolam or other muscle relaxants in reducing postoperative analgesic requirements?
Are there specific biomarkers like inflammatory cytokines or genetic polymorphisms predicting Tizanidine efficacy in breast surgery patients?
What adverse events are associated with preoperative Tizanidine use and how are they managed in surgical settings?
What combination therapies involving Tizanidine and local anesthetics show promise for enhanced postoperative pain control in breast procedures?