Effects of Vaginal Progesterone on Prevention of Preterm Delivery in Pregnant Women with Prior Spontaneous Preterm Birth

Completed

• Conditions: Preterm Delivery in Pregnant Women with Prior Spontaneous Preterm Birth; Vaginal progesterone , Prevention of Preterm Delivery, Prior Spontaneous Preterm Birth

• Registration Number: TCTR20220527007
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-04-18
• Study Start: 2022-05-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 82

Inclusion Criteria

1.Singleton pregnancy
2.History of Prior Spontaneous Preterm Birth
3.First visit at antenatal care unit of Rayong hospital before 16 weeks gestational age
4. Use vaginal progesterone

Exclusion Criteria

1.Start vaginal progesterone after gestational age 18 week
2. Loss follow up or denied use vaginal progesterone continueusly
3. The Fetus had severe anormally or genetic syndrome that need temination of prenancy
4. Problem of cervix uteri or Uterus such as congenital malformaion, Status post LEEP, Emdometriosis of uterus
5.Obstretric complications that need temination of prenancy such as Severe preeclampsia, Fetal distress
6.Medical complications that need temination of prenancy such as heart failure, servere pulmonary disease
7.Contraindication for use Progesterone

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of preterm delivery After the last pregnant woman gives birth Percentage

Secondary Outcome Measures

Name	Time	Method
Compare Gestational age(GA) of delivery with prior GA of preterm delivery After the last pregnant woman gives birth Mean differrent ,Changes of cervical length every 4 weeks of gestation Cervical length (CMs),Orther Risk fectors may influence preterm delivery Factor during ANC Factor (Personal characteristics)