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effect of sprint exercise in prediabetics.

Not Applicable
Completed
Conditions
Health Condition 1: null- Prediabetes: Impaired fasting glucose
Registration Number
CTRI/2013/03/003490
Lead Sponsor
Deepmala Deore
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

1) Prediabetes: Impaired fasting glucose (IFG) - FPG 100-125 mg/dl OR Impaired glucose tolerance((IGT)- 2hr PPG 140-199mg/dl

2) Age group: 25 to 40 years.

3) Asymptomatic males and females with a normal baseline ECG

Exclusion Criteria

1.Resting blood pressure greater than or equal to 160/100 mm Hg

2.Triglycerides greater than or equal to 500 mg/dL

3.Factors that may limit adherence to intervention or affect conduct of the trial such as lack of time, amount of travel, and/or work or family stressors

4.Unable or willing to communicate with staff, to provide written informed consent, or accept the randomized assignment

5.Failure to complete behavioral run-in and baseline testing

6.Not physically capable of performing the exercise required of the study protocols

7.Plans to be away >4 weeks in the next 6 months

8.Lack of support from primary health care provider or family members

9.Signficant weight loss in the past year ( >20 kg) or current use of weight loss medications or History of bariatric surgery within last 3 years

10.Current diagnsis of schizophrenia, or other psychotic disorders, or bipolar disorder

11.Other temporary intervening event, such as sick spouse, bereavement, or recent move

12.Other medical, psychiatric, or behavioral limitations that in the view of the principal investigator may interfere with study participation or the ability to follow the intervention protocol

13.Underlying diseases or conditions likely to limit lifespan and/or affect the safety of the intervention

14.Self-reported HIV or tuberculosis

15.History or evidence of serious arrhythmias, cardiomyopathy, congestive heart failure, aortic aneurysm, or heart transplantation

16.Renal disease: currently receiving dialysis

17.Type I diabetes mellitus

18.Type 2 diabetes mellitus, defined as: Fasting plasma glucose levels greater than or equal to 126 mg/dL 2-hour postprandial Oral Glucose Tolerance Test results greater than or equal to 200 mg/dL

19.Any other medical condition or disease that is life threatening or that can interfere with or be aggravated by exercise

20.Chronic obstructive lung disease, peripheral vascular disease or angina that limits ability to follow exercise protocol

21.Advanced neuropathy or retinopathy

22.Consuming alcoholic beverages, Smoker or have used nicotine/tobacco products within the last 12 months.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To compare the effects of 6 weeks of traditional aerobic exercise and sprint interval training on anxiety & stress as measured by DASS scale in subjects of Prediabetes.Timepoint: before start of study, weeks 6 and 3 months.
Secondary Outcome Measures
NameTimeMethod
To compare the effects of 6 weeks of aerobic training and Sprint Interval Training on biochemical markers of stress i.e. serum cortisol, serum cholesterol and blood urea nitrogen in subjects of PrediabetesTimepoint: before start of study, weeks 6 and 3 months.
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